Yes, I only have Runemate installed on one computer and I'm the only one running it. It works for a few days at a time, then it gives the error for a couple more days, then it works again. Very odd.
I keep getting the "more than two instances running" error. Waiting the 15 minutes did not fix it (Waiting 2+ hours did not fix it either). I restarted my computer multiple times and that did not fix the problem either. Please help!