Have used trial, Full automation and prayer only. 
Trial gets the early rounds done easily, is hit and miss in the mid rounds, thought I had the setup clocked once it hit round 53 with no issues.
Went to full automation for a full run whilst watching with the same setup. Prayers regularly mess up and hardly ever tries to safespot, tries to brute force it. 
Prayer only, the same, flicks prayers like crazy except when it actually matters. Had it flicking protect from ranged on melee only rounds.
Reading other reviews, looks to be some setups work for some and not others. Would benefit from an update.